Genotoxic Effects of Malathion in Chick in Vivo Micronucleus Assay.
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چکیده
منابع مشابه
Genotoxic and Antigenotoxic Activity of Silymarin by an In Vivo Bone Marrow Micronucleus Assay and Comet Assay
Introduction: Silymarin is obtained from Silybum marianum (milk thistle), an edible plant that has long been used medicinally for the treatment of liver-related disorders. Silymarin is a powerful hepatoprotective and antioxidant but the anticlastogenic activity, which is an important aspect of its cancer chemoprevention is not known hence the present investigation was carried out to study its...
متن کاملGenotoxic effects of oestrogens in breast cells detected by the micronucleus assay and the Comet assay.
Cumulative exposure to oestrogen has been linked to increased risk of breast cancer. Whilst oestrogens induce cancers in rodent bioassays it is unclear whether the mechanisms involved are genotoxic and/or epigenetic. The cytokinesis block micronucleus (CBMN) and the alkaline single cell-gel electrophoresis 'Comet' assays were used to examine MCF-7 cells for chromosomal damage and DNA single-str...
متن کاملMicronucleus assay- an early diagnostic tool to assess genotoxic changes in tobacco and related habits
Objective: Micronuclei are induced in cells by a variety of substances, like UV radiation, infrared rays, X-radiations, and chemicals. Among them tobacco- specific nitrosamines have been reported to be potent mutagenic agents which are thought to be responsible for the induction of chromosomal aberrations resulting in production of micronuclei. The main aim of our study is to compare MN frequen...
متن کاملgenotoxic and antigenotoxic activity of silymarin by an in vivo bone marrow micronucleus assay and comet assay
introduction: silymarin is obtained from silybum marianum (milk thistle), an edible plant that has long been used medicinally for the treatment of liver-related disorders. silymarin is a powerful hepatoprotective and antioxidant but the anticlastogenic activity, which is an important aspect of its cancer chemoprevention is not known hence the present investigation was carried out to study its a...
متن کاملGenotoxic effects of textile printing dye exposed workers in India detected by micronucleus assay.
The textile printing industry in South India employs a great number of workers that may possibly be exposed to toxic compounds. In the present study, subjects from textile printing units were investigated for the presence of genetic damage in their peripheral blood lymphocytes using micronucleus assay. Proliferation was also investigated using a nuclear division index. It was found that the mic...
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ژورنال
عنوان ژورنال: CYTOLOGIA
سال: 2002
ISSN: 0011-4545,1348-7019
DOI: 10.1508/cytologia.67.53